Functional comparisons of the virus sensor RIG-I from humans, the microbat Myotis daubentonii, and the megabat Rousettus aegyptiacus, and their response to SARS-CoV-2 infection
A. Schoen, M. Hölzer, M. Müller, C. Drosten, M. Marz, B. Lamp, F. Weber
This study functionally compares RIG-I from microbats, megabats, and humans, showing similar antiviral function and SARS-CoV-2 sensing ability in humans and megabats but not microbats.
bioRxiv · Feb 8, 2023 · PreprintImmunology