M. Müller

This paper uses human induced pluripotent stem cell-derived macrophages to model Leishmania donovani infection and test drug efficacy, showing comparable results to mouse macrophages.

The paper investigates how PHR1 and PHL1 mediate plant responses to high light by regulating Pi signaling and lipid metabolism.

This study functionally compares RIG-I from microbats, megabats, and humans, showing similar antiviral function and SARS-CoV-2 sensing ability in humans and megabats but not microbats.

The paper studies gene flow and admixture between Fagus sylvatica and Fagus orientalis in a German forest using molecular markers to determine the origin and direction of genetic exchange.

This study uses live-cell imaging to show that antiviral response activation varies in timing and strength based on viral replication dynamics and signaling pathway strength.

This study shows that influenza A virus worsens Group A Streptococcus infection in mice by reducing anti-bacterial inflammatory responses in macrophages.

This paper evaluates a stabilized carbocyclic Decitabine analogue, showing it effectively inhibits DNMT1 and induces more DNA damage in cancer cells with less toxicity.

This study shows that type I and type II interferons induce similar epigenomic and transcriptional changes in macrophages, including 3D chromatin rearrangements and increased DNA accessibility at ISG loci.

The paper introduces a modular structured illumination microscope (SIM) called HIT-SIM that enhances existing fluorescence microscopes with fast super-resolution imaging capabilities.

The paper identifies NamZ as an exo-{beta}-N-acetylmuramidase in Bacillus subtilis, showing its role in peptidoglycan degradation and proposing it as a founding member of a new family of hexosaminidases.

This paper develops a deep-learning method to denoise and reconstruct SR-SIM images, improving image quality and robustness across varying noise levels and microscope settings.

This study uses 3D imaging to show SARS-CoV-2 preferentially infects the upper respiratory tract of ferrets with a focal pattern in nasal turbinates.

This paper presents simulation frameworks for DMD-based illumination systems in structured illumination microscopy, addressing diffraction effects and system alignment.

This paper develops a cost-effective, high-speed structured illumination microscopy system using DMDs and CMOS cameras to visualize live cell dynamics with super-resolution.

This paper introduces a multi-plane SR-SIM technique to enable fast 3D live cell imaging using an image-splitting prism and additional camera.

The paper identifies shared targets of Ypk1, PKA, and Sch9 by comparing phospho-proteomes under chemical inhibition, revealing Ypk1's role in phosphorylating and activating Nth1.