BioengineeringbioRxiv
Accelerating Strain Engineering using Desorption Electrospray Ionization-Imaging Mass Spectrometry and Untargeted Molecular Analysis of Intact Microbial Colonies.
B. M. Ellis, P. Babele, J. C. May…·J. A. McLean
This paper develops a DESI-IMS assay to rapidly phenotype engineered E. coli strains by analyzing their metabolomes, identifying strategies for strain optimization.
DOI 10.1073/pnas.2109633118