BiochemistrybioRxiv
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
K. Pedram, D. J. Shon, G. S. Tender…·C. R. Bertozzi
This paper designs a mucin-selective protease conjugated to a nanobody to degrade cancer-associated mucins, showing reduced tumor growth in mouse models.
DOI 10.1038/s41587-023-01840-6