Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis
B. Maffei, M. Laverriere, Y. Wu, S. Triboulet, S. Perrinet, M. Duchateau, M. Matondo, R. L. Hollis, C. Gourley, J. Rupp, J. W. Keillor, A. Subtil
This study shows that TG2 activation during Chlamydia trachomatis infection enhances glucose uptake and hexosamine biosynthesis to support bacterial growth.
bioRxiv · May 10, 2019Microbiology