Author

A. Subtil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Y. Wu· 3 shared B. Niragire· 2 shared M. Duchateau· 2 shared M. Matondo· 2 shared S. Perrinet· 2 shared S. Triboulet· 2 shared A. Di Cicco· 1 shared A. G. Torres· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

Y. Wu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Intracellular growth of Chlamydia trachomatis leads to global histone hypermethylation by impairing demethylation

C. I. Charendoff, F. V. Louchez, Y. Wu, L. Dolat, G. Velasco, S. Perrinet, A. G. Torres, L. Blanchet, M. Duchateau, Q. G. Gianetto, M. Matondo, L. Del Maestro, S. Ait-Si-Ali, F. Bonhomme, G. Millot, , A. Subtil

This study shows that Chlamydia trachomatis infection causes global histone hypermethylation by inhibiting demethylation, leading to altered transcription and affecting infection outcomes.

bioRxiv · Jun 4, 2024Cell Biology

Chlamydia-driven ISG15 expression dampens the immune response of epithelial cells independently of ISGylation

Y. Wu, C. Liu, C. Tang, B. Niragire, Y. Levy-Zauberman, C. Adapen, T. Vernay, J. Hugueny, V. Baud, A. Subtil

This study shows that ISG15 expression in epithelial cells infected with Chlamydia trachomatis reduces inflammation and bacterial load without requiring ISGylation.

bioRxiv · May 27, 2024Microbiology

PI4P and BLOC-1 remodel endosomal membranes into tubules

R. A. Jani, A. Di Cicco, T. Keren-Kaplan, S. Vale-Costa, D. Hamaoui, I. Hurbain, F.-C. Tsai, M. Dimarco, A.-S. Mace, Y. Zhu, M. J. Amorim, P. Bassereau, J. S. Bonifacino, A. Subtil, M. S. Marks, , C. Delevoye

This study shows how PI4P and BLOC-1 coordinate to form and stabilize endosomal tubules, essential for membrane remodeling and pathogen trafficking.

bioRxiv · Oct 21, 2021Cell Biology

Acquisition of a type 3 secretion signal in an housekeeping enzyme shaped glycogen metabolism in Chlamydia

S. Triboulet, M. D. N'Gadjaga, B. Niragire, S. Köstlbacher, M. Horn, A. Subtil

The paper identifies a bacterial phosphoglucomutase (PGM) that converts glucose-1-phosphate to glucose-6-phosphate in Chlamydia, with glycogen metabolism linked to a type three secretion signal in the PGM gene.

bioRxiv · Oct 11, 2020Microbiology

Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis

B. Maffei, M. Laverriere, Y. Wu, S. Triboulet, S. Perrinet, M. Duchateau, M. Matondo, R. L. Hollis, C. Gourley, J. Rupp, J. W. Keillor, A. Subtil

This study shows that TG2 activation during Chlamydia trachomatis infection enhances glucose uptake and hexosamine biosynthesis to support bacterial growth.

bioRxiv · May 10, 2019Microbiology