Cell BiologybioRxiv
Polymerization of misfolded protein lowers CX3CR1 expression in human PBMCs
S. Tumpara, M. Ballmaier, S. Wrenger…·S. Janciauskiene
This study shows that polymerized misfolded Z-AAT protein reduces CX3CR1 expression on human PBMCs, suggesting a role for extracellular misfolded proteins in immune regulation.
DOI 10.7554/elife.64881