Multi-omics profiling of collagen-induced arthritis mouse model reveals early metabolic dysregulation via SIRT1 axis
L. Li, J. Freitag, C. Asbrand, B. Munteanu, B.-T. Wang, E. Zezina, M. Didier, G. Thill, C. Rocher, M. Herrmann, N. Biesemann
This study identifies early metabolic dysregulation in a mouse arthritis model through integrative metabolomics and RNA-seq, highlighting the SIRT1 axis as a potential therapeutic target.
Scientific Reports · Jul 12, 2022Peer-reviewedCell Biology