Author

M. Didier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1

Frequent Co-Authors

C. Rocher· 2 shared A. Carreras-Sureda· 1 shared A. Jacquet· 1 shared A. Kannt· 1 shared A.-C. Le Fevre· 1 shared B. Munteanu· 1 shared B.-T. Wang· 1 shared C. Asbrand· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

C. Rocher

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multi-omics profiling of collagen-induced arthritis mouse model reveals early metabolic dysregulation via SIRT1 axis

L. Li, J. Freitag, C. Asbrand, B. Munteanu, B.-T. Wang, E. Zezina, M. Didier, G. Thill, C. Rocher, M. Herrmann, N. Biesemann

This study identifies early metabolic dysregulation in a mouse arthritis model through integrative metabolomics and RNA-seq, highlighting the SIRT1 axis as a potential therapeutic target.

Scientific Reports · Jul 12, 2022Peer-reviewedCell Biology

S-acylation targets ORAI1 channels to lipid rafts for efficient Ca2+ signaling by T cell receptors at the immune synapse

A. Carreras-Sureda, L. Abrami, K. JI-Hee, M. Frieden, M. Didier, F. G. van der Goot, N. Demaurex

This study shows that S-acylation of ORAI1 channels at Cys143 by ZDHHC20 is essential for TCR signaling and Ca2+ flux at the immune synapse.

bioRxiv · Feb 3, 2021Biochemistry

A 3D human liver model of nonalcoholic steatohepatitis

M. Duriez, L. Hoet, A. Jacquet, S. Roche, M.-D. Bock, C. Rocher, G. Haussy, X. Vige, Z. Bocskei, T. Slavnic, V. Martin, J.-C. Guillemot, M. Didier, A. Kannt, C. Orsini, , A.-C. Le Fevre

The paper develops a 3D human liver model of nonalcoholic steatohepatitis that can be used for drug screening and disease study.

bioRxiv · Feb 7, 2020Cell Biology