Author

C. Rocher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 2 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:development & morphogenesis· 3 Organism:non-human primate· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Le Bivic· 3 shared C. Borchiellini· 3 shared E. Renard· 3 shared A. Vernale· 2 shared M. Didier· 2 shared N. Brouilly· 2 shared A. Ereskovsky· 1 shared A. Jacquet· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersEvolutionary Biology

A. Le Bivic

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Author profile →

5 papers

Recent·Most cited

The compact genome of the sponge Oopsacas minuta (Hexactinellida) is lacking key metazoan core genes

S. Santini, Q. Schenkelaars, C. Jourda, M. Duschene, H. Belahbib, C. Rocher, M. Selva, A. Riesgo, M. Vervoort, S. P. Leys, L. Kodjabachian, A. Le Bivic, C. Borchiellini, J.-M. Claverie, E. Renard

This study analyzes the genome of the glass sponge Oopsacas minuta, revealing its compact size and loss of key metazoan genes, suggesting unique evolutionary adaptations.

bioRxiv · Jul 26, 2022 · PreprintEvolutionary Biology

Multi-omics profiling of collagen-induced arthritis mouse model reveals early metabolic dysregulation via SIRT1 axis

L. Li, J. Freitag, C. Asbrand, B. Munteanu, B.-T. Wang, E. Zezina, M. Didier, G. Thill, C. Rocher, M. Herrmann, N. Biesemann

This study identifies early metabolic dysregulation in a mouse arthritis model through integrative metabolomics and RNA-seq, highlighting the SIRT1 axis as a potential therapeutic target.

Scientific Reports · Jul 12, 2022Peer-reviewedCell Biology

Evolution of mechanisms controlling epithelial morphogenesis across animals: new insights from dissociation - reaggregation experiments in the sponge Oscarella lobularis.

A. Vernale, M. M. Prunster, F. Marchiano, H. Debost, N. Brouilly, C. Rocher, D. Massey Harroche, E. RENARD, A. Le Bivic, B. H. Habermann, C. Borchiellini

The paper investigates epithelial morphogenesis in the sponge Oscarella lobularis using dissociation-reaggregation experiments, revealing conserved molecular mechanisms between sponges and bilaterians.

bioRxiv · Mar 22, 2021Evolutionary Biology

The buds of Oscarella lobularis (Porifera): a new convenient model for sponge cell and developmental biology

C. Rocher, A. Vernale, L. Fierro-Constain, N. Sejourne, S. Chenesseau, C. Marschal, E. Le Golf, M. Dutilleul, C. Matthews, F. Marschal, N. Brouilly, D. Massey-Harroche, A. Ereskovsky, A. Le Bivic, C. Borchiellini, E. Renard

This paper introduces a new sponge model, Oscarella lobularis buds, for studying cell biology and developmental processes with modern experimental techniques.

bioRxiv · Jun 23, 2020 · PreprintZoology

A 3D human liver model of nonalcoholic steatohepatitis

M. Duriez, L. Hoet, A. Jacquet, S. Roche, M.-D. Bock, C. Rocher, G. Haussy, X. Vige, Z. Bocskei, T. Slavnic, V. Martin, J.-C. Guillemot, M. Didier, A. Kannt, C. Orsini, , A.-C. Le Fevre

The paper develops a 3D human liver model of nonalcoholic steatohepatitis that can be used for drug screening and disease study.

bioRxiv · Feb 7, 2020Cell Biology