Author

B. Niederoest

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

A. A. Hussien· 2 shared J. G. Snedeker· 2 shared F. Renoux· 1 shared J. Foolen· 1 shared M. Bollhalder· 1 shared N. Goedecke· 1 shared O. Distler· 1 shared R. Knell· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersCell Biology

A. A. Hussien

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedMar 13, 2026

Sustained mechanical tension governs fibrogenic activation of tendon stromal cells in systemic sclerosis

A. A. Hussien, R. Knell, F. Renoux…·J. G. Snedeker

This study shows that sustained mechanical tension drives fibrogenic activation of tendon stromal cells in systemic sclerosis, revealing a feedback loop between fibroblasts and ECM stiffening.

DOI 10.1038/s41467-026-70395-2

humanexperimental assay

𝕏 PostBluesky

BioengineeringbioRxivMay 27, 2021

The stiffness-sensitive transcriptome of human tendon stromal cells

A. A. Hussien, B. Niederoest, M. Bollhalder…·J. G. Snedeker

This study maps how matrix stiffness influences the transcriptome of human tendon stromal cells, revealing distinct gene expression programs at different stiffness levels.

DOI 10.1002/adhm.202101216

humanbulk RNA-seq

𝕏 PostBluesky