Chlamydia-driven ISG15 expression dampens the immune response of epithelial cells independently of ISGylation
Y. Wu, C. Liu, C. Tang, B. Niragire, Y. Levy-Zauberman, C. Adapen, T. Vernay, J. Hugueny, V. Baud, A. Subtil
This study shows that ISG15 expression in epithelial cells infected with Chlamydia trachomatis reduces inflammation and bacterial load without requiring ISGylation.
bioRxiv · May 27, 2024Microbiology