MYB insufficiency disrupts proteostasis in hematopoietic stem cells leading to age-related neoplasia
M. L. Clarke, R. B. Lemma, D. S. Walton, G. Volpe, B. Noyvert, O. S. Gabrielsen, J. Frampton
This study shows that Myb insufficiency in mice leads to age-related hematological diseases, suggesting proteostasis disruption as a mechanism.
bioRxiv · Sep 4, 2021Cancer Biology