Cancer BiologybioRxiv
MYB insufficiency disrupts proteostasis in hematopoietic stem cells leading to age-related neoplasia
M. L. Clarke, R. B. Lemma, D. S. Walton…·J. Frampton
This study shows that Myb insufficiency in mice leads to age-related hematological diseases, suggesting proteostasis disruption as a mechanism.
DOI 10.1182/blood.2022019138