Spatial analysis of ligand-receptor interaction in skin cancer at genome-wide and single-cell resolution
M. Tran, S. Yoon, M. T. Siok, S. Andersen, P. Lam, B. Purdue, A. Raghubar, S. J. Hanson, K. Devitt, K. Jones, S. Walters, Z. K. Tuong, A. Kulasinghe, J. Monkman, P. H. Soyer, , Q. Nguyen
The paper develops a toolbox to study cancer-immune cell communication using multimodal data and a computational method called STRISH, validated on basal and squamous cell carcinomas.
bioRxiv · Sep 10, 2020Cancer Biology