Microgroove substrates unveil topography-driven, dynamic 3D nuclear deformations
C. Leclech, B. Roellinger, J. Frederick, K. Mamchaoui, C. Coirault, A. I. Barakat
This study uses microgroove substrates to show that adherent cells exhibit dynamic 3D nuclear deformations driven by adhesion, with implications for diagnosing nuclear mechanical disorders.
bioRxiv · Feb 2, 2024 · PreprintCell Biology