2'3'-cGAMP triggers a STING and NF-κB dependent broad antiviral response in Drosophila
H. Cai, A. Holleufer, B. Simonsen, J. Schneider, A. Lemoine, H.-H. Gad, J. Huang, J. Huang, D. Chen, T. Peng, J. T. Marques, R. Hartmann, N. E. Martins, J.-L. Imler
This study shows that 2'3'-cGAMP activates dSTING and NF-κB to trigger a broad antiviral response in Drosophila, independent of autophagy and RNAi pathways.
bioRxiv · Nov 27, 2019Immunology