Author

B. Sorum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:electrophysiology· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

S. G. Brohawn· 3 shared R. A. Rietmeijer· 2 shared A. Kotecha· 1 shared B. Li· 1 shared C. M. Hoel· 1 shared D. B. Toso· 1 shared D. M. Bautista· 1 shared D. M. Kern· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiophysics

S. G. Brohawn

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pressure and ultrasound activate mechanosensitive TRAAK K+ channels through increased membrane tension

B. Sorum, T. Docter, V. Panico, R. A. Rietmeijer, S. G. Brohawn

This study investigates how TRAAK K+ channels respond to mechanical tension and ultrasound, showing high sensitivity and a graded response profile.

bioRxiv · Jan 11, 2023 · PreprintBiophysics

Cryo-EM structure of the SARS-CoV-2 3a ion channel in lipid nanodiscs

D. M. Kern, B. Sorum, S. S. Mali, C. M. Hoel, S. Sridharan, J. P. Remis, D. B. Toso, A. Kotecha, D. M. Bautista, S. G. Brohawn

This study presents the cryo-EM structure of SARS-CoV-2 3a ion channel in lipid nanodiscs, revealing its functional properties and evolutionary conservation.

Nature Structural & Molecular Biology · Jun 22, 2021Peer-reviewedBiophysics

Physical basis for distinct basal and mechanically-gated activity of the human K+ channel TRAAK

R. A. Rietmeijer, B. Sorum, B. Li, S. G. Brohawn

This study identifies structural and functional differences between basal and mechanically-gated activity in the TRAAK K+ channel, explaining how a single channel can produce distinct modes of activity.

bioRxiv · Jun 4, 2021Biophysics