Rev-erb-α controls skeletal muscle calcium homeostasis through myoregulin repression: implications in Duchenne Muscular Dystrophy
A. Boulinguiez, C. Duhem, A. Mayeuf-Louchart, B. Pourcet, Y. Sebti, K. Kondratska, V. Montel, S. Delhaye, Q. Thorel, J. Beauchamp, A. Hebras, M. Gimenez, M. Couvelaere, M. Zecchin, L. Ferri, , S. Lancel
This study shows Rev-erb-α regulates skeletal muscle calcium homeostasis by repressing Myoregulin, and its activation improves SR calcium handling in Duchenne Muscular Dystrophy models.
bioRxiv · Apr 22, 2021 · PreprintCell Biology