PhysiologybioRxiv
The hepatic compensatory response to elevated systemic sulfide promotes diabetes
R. N. Carter, M. T. G. Gibbins, M. E. Barrios-Llerena…·N. M. Morton
This study shows that mice lacking the sulfide oxidation pathway enzyme TST exhibit metabolic abnormalities despite insulin sensitization, highlighting TST's role in hepatic metabolism and potential implications for sulfide-donor therapies.
DOI 10.1016/j.celrep.2021.109958