Cancer BiologybioRxiv
XPC deficiency increases risk of hematologic malignancies through mutator phenotype and characteristic mutational signature
A. A. Yurchenko, I. Padioleau, B. T. Matkarimov…·S. Nikolaev
This study shows XPC deficiency leads to higher mutation rates and specific mutational signatures in hematologic malignancies, increasing cancer risk through a mutator phenotype.
DOI 10.1038/s41467-020-19633-9