BiochemistrybioRxiv
A thermostable Cas9 with increased lifetime in human plasma
L. Harrington, D. Paez-Espino, J. S. Chen…·J. A. Doudna
This paper describes a thermostable Cas9 variant from Geobacillus stearothermophilus that functions at higher temperatures and has increased stability in human plasma, expanding CRISPR-Cas9 applications.
DOI 10.1038/s41467-017-01408-4