Author

B. Tofig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

R. Damoiseaux· 2 shared A. A. Gholkar· 1 shared A. Soragni· 1 shared D. Elashoff· 1 shared E. F. Velasquez· 1 shared I. Ramirez· 1 shared J. Huang· 1 shared J. J. Hong· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

R. Damoiseaux

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2 papers

Recent·Most cited

DUSP7 Regulates the Activity of ERK2 to PromoteProper Chromosome Alignment During Cell Division

X. Guo, Y. A. Garcia, I. Ramirez, E. F. Velasquez, L. W. Gao, A. A. Gholkar, J. P. Whitelegge, B. Tofig, R. Damoiseaux, J. Z. Torres

This study shows DUSP7 regulates ERK2 activity to ensure proper chromosome alignment during cell division, preventing aneuploidy and tumorigenesis.

bioRxiv · Jun 5, 2020Cell Biology

A simple high-throughput approach identifies actionable drug responses in patient-derived tumor organoids

N. Phan, J. J. Hong, B. Tofig, M. Mapua, D. Elashoff, N. A. Moatamed, J. Huang, S. Memarzadeh, R. Damoiseaux, A. Soragni

This paper introduces a high-throughput method for drug screening using tumor organoids and identifies effective drugs for ovarian cancer within a week of surgery.

bioRxiv · Aug 13, 2018Cancer Biology