Cul3 substrate adaptor SPOP targets Nup153 for degradation
This study identifies Nup153 as a novel substrate of SPOP, showing SPOP targets Nup153 for degradation and affects nuclear envelope localization of Mad1.
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5 papers
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This study identifies Nup153 as a novel substrate of SPOP, showing SPOP targets Nup153 for degradation and affects nuclear envelope localization of Mad1.
X. Guo, Y. A. Garcia, I. Ramirez…·J. Z. Torres
This study shows DUSP7 regulates ERK2 activity to ensure proper chromosome alignment during cell division, preventing aneuploidy and tumorigenesis.
Y. A. Garcia, E. F. Velasquez, L. A. Gao…·J. Z. Torres
The paper uses proximity proteomics to map the spatial associations of core SAC proteins during prometaphase, revealing known and novel interactions.
A. A. Gholkar, S. Schmollinger, E. F. Velasquez…·J. Z. Torres
This study shows Parkin binds and ubiquitylates lactotransferrin to regulate iron homeostasis, linking Parkin dysfunction to Parkinson's disease.