β-Catenin tumour-suppressor activity depends on its ability to promote Pro-N-Cadherin maturation
A. Herrera, A. Menendez, B. Torroba, S. Pons
This study shows that β-Catenin promotes Pro-N-Cadherin maturation, which is necessary for apical junction formation and apico-basal polarity, and that this activity suppresses tumor formation in neural stem cells.
bioRxiv · Mar 8, 2019 · PreprintCell Biology