BioengineeringbioRxiv
Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines
S. Prithiviraj, A. Garcia Garcia, K. Linderfalk…·P. E. Bourgine
This study uses CRISPR/Cas9 to edit human mesenchymal stem cells to produce engineered extracellular matrices with modified VEGF and RUNX2 expression, showing altered osteogenic properties.
DOI 10.7554/elife.96941