Mesothelial Plasticity Specifies a Pleural Immune Circuit that Orchestrates Lung Regeneration
Le Xu, Kevin H. Chen, Barsha Dash, Bingpeng Yao, Rongbo Li, Xingan Wang, Zihe Zhou, Vincent Yu, Rebecca J. Salamon, Pushpinder Bawa, Minzhe Guo, Zea Borok, Darrell N. Kotton, Oliver Eickelberg, Marta Bueno, Xin Sun
The paper identifies mesothelial cell plasticity as a key determinant of regenerative versus degenerative lung repair by comparing pneumonectomy and chronic lung allograft dysfunction models.
bioRxiv · Jun 29, 2026 · PreprintDevelopmental Biology