Evolutionary BiologybioRxiv
The molecular chaperone DnaK accelerates protein evolution
Jose Aguilar-Rodriguez, Beatriz Sabater-Munoz, Victor Berlanga…·Mario A. Fares
This study shows that the Hsp70 chaperone DnaK in E. coli buffers mutations in its client proteins, leading to faster evolutionary rates in strongly interacting clients.
DOI 10.1093/gbe/evw176