Author

Begoña Lecube-Azpeitia

Harvard University

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Synthetic Biology· 1

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Approach:experimental assay· 1

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Christopher D. JohnstoniD· 1 shared George McDonald ChurchiD· 1 shared Javier F. JuáreziD· 1 shared Stuart L. Brown· 1 shared

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2018-2018 · peak 1/yr

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Christopher D. JohnstonORCID

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Synthetic BiologyNature CommunicationsPeer-reviewedJul 31, 2018

Biosensor libraries harness large classes of binding domains for allosteric transcription regulators

Javier F. Juárez, Begoña Lecube-Azpeitia, Stuart L. Brown…·George McDonald Church

The paper presents a strategy to construct and test chimeric transcription factor libraries using periplasmic binding proteins and DNA-binding domains to create biosensors for small molecule sensing.

66 citationstop 4%

experimental assay

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