PhysiologyCirculation ResearchPeer-reviewed
Disturbed repolarisation-relaxation coupling during acute ischaemia permits systolic mechano-arrhythmogenesis.
Breanne Ashleigh Cameron, Peter Baumeister, Tarek Lawen…·Thomas Alexander Quinn
This study shows that disturbed repolarisation-relaxation coupling during acute ischaemia increases systolic mechano-arrhythmogenesis, which can be mitigated by restoring coupling or targeting calcium, TRPA1, or ROS.
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