Rémi Peyronnet

This study shows that disturbed repolarisation-relaxation coupling during acute ischaemia increases systolic mechano-arrhythmogenesis, which can be mitigated by restoring coupling or targeting calcium, TRPA1, or ROS.

This study compares stretch-activated channel activity in bone marrow-derived and cardiac tissue-resident macrophages, finding that Piezo1 activity is absent in the latter.

This study shows that TRPA1 activation and disrupted repolarisation-relaxation coupling during systole contribute to mechano-arrhythmogenesis in ischaemic conditions.

This study examines the structure and dynamics of cardiac fibroblast nanotubes in human atrial tissue and cell lines, showing their role in intercellular communication and ECM interaction.

This study identifies two stretch-activated ion channels, Piezo1 and BKCa, in human atrial fibroblasts and shows their differential regulation in atrial fibrillation.