Author

Beini Zhang

University of Toronto

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Synthetic Biology· 1

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Research Focus:benchmarking· 1 Organism:E. coli· 1 Approach:statistical model· 1

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Kaushik RajiD· 1 shared Radhakrishnan MahadevaniD· 1 shared William T. Z. Wong· 1 shared

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2022-2022 · peak 1/yr

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Kaushik RajORCID

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Synthetic BiologybioRxivPreprintMar 31, 2022

Design principles for bistable genetic switches emerge from a growth-dependent speed-robustness trade-off

Kaushik Raj, William T. Z. Wong, Beini Zhang, Radhakrishnan Mahadevan

The paper identifies design principles for bi-stable genetic switches by analyzing the trade-off between switching speed and robustness, validated experimentally in E. coli.

DOI 10.1101/2022.03.31.486579

E. colistatistical model

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