Cancer BiologybioRxivPreprint
Cancer associated fibroblasts drive epithelial to mesenchymal transition and classical to basal change in pancreatic ductal adenocarcinoma cells with loss of IL-8 expression
Samantha R. Guinn, Brayan Perez, Joseph A. Tandurella…·Jacquelyn W. Zimmerman
The paper investigates how cancer-associated fibroblasts (CAF) influence tumor cell behavior in pancreatic ductal adenocarcinoma by driving EMT and altering cell subtypes, with IL-8 playing a key modulatory role.
2 citations