Author
Johns Hopkins UniversityORCID 0000-0002-6044-2631Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Yeonju Cho, Jae Woo Lee, Sarah M. Shin…·Won Jin Ho
The paper introduces FunCN, a method to analyze cellular neighborhoods in PDAC, revealing distinct immune interactions in primary and metastatic sites.
Samantha R. Guinn, Brayan Perez, Joseph A. Tandurella…·Jacquelyn W. Zimmerman
The paper investigates how cancer-associated fibroblasts (CAF) influence tumor cell behavior in pancreatic ductal adenocarcinoma by driving EMT and altering cell subtypes, with IL-8 playing a key modulatory role.
Eloïse M. Grasset, Atul M. Deshpande, Jae Woo Lee…·Won Jin Ho
The paper uses spatial analysis to show metastasis-initiating cancer cells in breast tumors are closely associated with specific macrophage subtypes, suggesting these interactions promote metastasis.
Satoru Morita, Tomofumi Ando, Hiroto Kikuchi…·Dan Gabriel Duda
Liver fibrosis limits the survival benefit of multikinase inhibitor immunotherapy in hepatocellular carcinoma by promoting innate immune-mediated hepatotoxicity despite preserved tumor control.
Daniel H. Shu, Won Jin Ho, Luciane T. Kagohara…·Mark Yarchoan
This study examines TLS in HCC treated with neoadjuvant immunotherapy, finding TLS correlate with better outcomes and show distinct morphological and functional features in tumor regression.