Author

Bennett E. Vogt

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

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Anna G. GreeniD· 1 shared Charlotta P.I. Schärfe· 1 shared Debora S. MarksiD· 1 shared John M. Nicoludis· 1 shared Rachelle GaudetiD· 1 shared

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2016-2016 · peak 1/yr

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1 shared paperBiochemistry

Anna G. GreenORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivJul 12, 2016

Antiparallel protocadherin homodimers use distinct affinity- and specificity mediating regions in cadherin repeats 1-4

John M. Nicoludis, Bennett E. Vogt, Anna G. Green…·Rachelle Gaudet

The paper determines the structure of human PcdhYB3's antiparallel EC1-4 homodimer and shows that subfamily-specific specificity arises from loop region diversification, while EC1/EC4 interfaces use hydrophobic interactions for non-selective dimerization.

DOI 10.7554/elife.18449

humanstructural biology

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