GenomicsbioRxivPreprint
Plasma derived cell-free mitochondrial DNA originates mainly from circulating cell-free mitochondria
Benoit Roch, Ekaterina Pisareva, Cynthia Sanchez…·Alain Roger Thierry
The paper investigates the origin of circulating mitochondrial DNA (cir-mtDNA) and finds it primarily comes from extracellular mitochondria and vesicles, with a significant reduction when platelet activation is avoided.
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