Systems BiologybioRxivPreprint
Tissue Level Profiling of SARS-CoV-2 antivirals in mice to predict their effects: comparing Remdesivir's active metabolite GS-441 524 vs. the clinically failed Hydroxychloroquine
Oliver Scherf‐Clavel, Edith Kaczmarek, Martina Kinzig…·F. Sörgel
This study compares the tissue distribution and pharmacokinetics of GS-441 524 and hydroxychloroquine in mice to assess their potential antiviral efficacy against SARS-CoV-2.
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