Author

Bonnie Higgins

Pennsylvania State University

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Genomics· 1

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Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

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Barbara ArbeithuberiD· 1 shared Francesca ChiaromonteiD· 1 shared Irene Tiemann‐BoegeiD· 1 shared Kate Anthony· 1 shared Kateryna D. MakovaiD· 1 shared Omar Josef ShebliD· 1 shared Peter OppeltiD· 1 shared Thomas EbneriD· 1 shared

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Recent·Most cited

GenomicsScience AdvancesPeer-reviewedAug 6, 2025

Mitochondrial DNA mutations in human oocytes undergo frequency-dependent selection but do not increase with age

Barbara Arbeithuber, Kate Anthony, Bonnie Higgins…·Kateryna D. Makova

The paper detects mtDNA mutations in oocytes, blood, and saliva across ages and finds mutations increase in blood and saliva but not in oocytes, with age-related differences in mutation frequency distribution.

19 citationstop 3%

humanDNA methylation

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