Author

Brad J. Geddes

Proteostasis Therapeutics (United States)

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Neuroscience· 1

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Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Arun ThiruvalluvaniD· 1 shared Carlos SpichigeriD· 1 shared Christian Enrique González-BillaultiD· 1 shared Claudio A. HetziD· 1 shared Cristian SaqueliD· 1 shared Daniel R. Henríquez· 1 shared Di WuiD· 1 shared Felipe A. CourtiD· 1 shared

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2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Arun ThiruvalluvanORCID

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1 paper

Recent·Most cited

NeuroscienceActa NeuropathologicaPeer-reviewedJul 8, 2020

Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates

Paula García-Huerta, Paulina Troncoso-Escudero, Di Wu…·Claudio A. Hetz

This study identifies IGF2 as a disease modifier that reduces intracellular protein aggregates by promoting their extracellular disposal in Huntington's disease models.

70 citationstop 3%

humanmouse

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