Molecular BiologyPLoS PathogensPeer-reviewed
The Plasmepsin-Piperaquine Paradox Persists
Breanna Walsh, Robert L. Summers, Gabriel W. Rangel…·Selina E. R. Bopp
This study uses CRISPR/Cas9 to knockout plasmepsin II and III in Cambodian malaria parasites, showing increased sensitivity to piperaquine and linking plasmepsin gene copy numbers to PPQ resistance.
4 citations