GenomicsbioRxivPreprint
Early Alzheimer's disease pathology in human cortex is associated with a transient phase of distinct cell states
Vahid Gazestani, Tushar Kamath, Naeem M. Nadaf…·Evan Z. Macosko
The paper identifies a transient hyperactive neuronal state in early Alzheimer's disease using single-nucleus transcriptomics from living patients.