MicrobiologyJCI InsightPeer-reviewed
Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease
Joseph W. Golden, Curtis R. Cline, Xiankun Zeng…·Jay W. Hooper
This study shows that human ACE2 transgenic mice infected with SARS-CoV-2 develop severe respiratory disease, with males more susceptible than females.
DOI 10.1172/jci.insight.142032