ImmunologybioRxivPreprint
An essential checkpoint for TLR9 signaling is release from 1 Unc93b1 in endosomes
Olivia Majer, Brian J Woo, Bo Liu…·Gregory M Barton
The paper identifies a mechanism by which TLR9 is restricted to endosomes through its association with Unc93b1, ensuring proper signaling and preventing autoimmunity.
DOI 10.1101/410092