ImmunologybioRxivPreprint
Reversible expansion of tissue macrophages in response to macrophage colony-stimulating factor (CSF1) transforms systemic metabolism to fuel growth.
Sahar Keshvari, Jesse J.R. Masson, Michelle Ferrari-Cestari…·Katharine M. Irvine
This study shows that CSF1 increases tissue macrophages and alters systemic metabolism, including glucose uptake and fat mobilization, with reversible effects on liver size and body composition.
DOI 10.1101/2023.05.17.538022