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Briana Branch

National Institutes of Health

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Approach:experimental assay· 1

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Francesco RaimondiiD· 1 shared Mariastella Cascone· 1 shared Ramiro Iglesias‐BartoloméiD· 1 shared Yao Zong YUANiD· 1 shared

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Cell BiologybioRxivPreprintOct 3, 2024

An improved TEAD dominant-negative protein inhibitor to study Hippo YAP1/TAZ-dependent transcription.

Briana Branch, Yao Zong YUAN, Mariastella Cascone…·Ramiro Iglesias‐Bartolomé

This study improves a dominant-negative TEAD inhibitor, TEADi, by modifying its binding domains to enhance its ability to block YAP1 and TAZ interactions with TEAD, revealing differences in their displacement mechanisms.

4 citations

experimental assay

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