BioengineeringbioRxivPreprint
Targeted suppression of type 1 interferon signaling during RNA delivery enhances vaccine-elicited immunity
Byungji Kim, Ryan Ramsey Hosn, Tanaka K. Remba…·Darrell J. Irvine
This study shows that co-delivering siRNA targeting IFNAR1 with RNA vaccines enhances antigen expression, immune cell infiltration, and antibody and T cell responses.
5 citations