GenomicsbioRxivPreprint
Unbiased identification of unknown cellular and environmental factors that mediate eQTLs using principal interaction component analysis
Martijn Vochteloo, Patrick Deelen, Britt Vink…·Lude Franke
This paper introduces PICALO, a method to identify unknown contexts influencing eQTLs, finding 31 and 21 PICs in blood and brain datasets, respectively, associated with cell type, RNA quality, and environmental factors.
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