Author

Brockton Keen

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Research Focus:drug response / drug discovery· 1 Approach:machine learning (classical)· 1

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Callie E. W. CrawfordiD· 1 shared George M. BurslemiD· 1 shared Jordi C. J. HintzeniD· 1 shared Sebastian Dilones· 1 shared Sydney Gordon· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperBiochemistry

Callie E. W. CrawfordORCID

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1 paper

Recent·Most cited

BiochemistryChemBioChemPeer-reviewedJun 24, 2026

Quinazolinone and Phthalazinone Inhibitors of the HDAC6/Ubiquitin Protein-Protein Interaction

Sydney Gordon, Jordi C. J. Hintzen, Sebastian Dilones…·George M. Burslem

The paper identifies and optimizes quinazolinone and phthalazinone inhibitors targeting the HDAC6 ZnF-UBD/ubiquitin interaction, using computational and experimental methods to improve their physicochemical properties and predict binding affinity.

1 citation

machine learning (classical)drug response / drug discovery

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