Author

Bruce A. Vallance

Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, BC Children’s Hospital Research Institute, University of British Columbia, Vancouver, Canada.

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Brendan DolaniD· 1 shared Brian R. WasikiD· 1 shared Caixia MaiD· 1 shared Clara A. Letef· 1 shared Colin R. ParrishiD· 1 shared Daniel ChouiD· 1 shared Elena LayuntaiD· 1 shared Emily HowardiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPhysiology

Brendan DolanORCID

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2 papers

Recent·Most cited

Cell BiologyiSciencePeer-reviewedOct 29, 2026

Intestinal epithelial Casd1 influences mucus sialic acid O-acetylation and tissue damage susceptibility toward large-intestinal mucosal insults.

Simin Jafaripour, Mackenzie Melvin, Megan Turluk…·Kirk Bergstrom

This study investigates the role of Casd1 in sialic acid O-acetylation of intestinal mucus and its impact on tissue damage susceptibility in mice.

DOI 10.1016/j.isci.2026.117978

mouseproteomics

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PhysiologybioRxivFeb 8, 2024

MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn's disease

Elena Layunta, Sofia Jäverfelt, Fleur C. van de Koolwijk…·Thaher Pelaseyed

The paper identifies MUC17 as a critical component of the small intestinal glycocalyx that is disrupted in Crohn's disease, leading to bacterial contact and epithelial defects.

DOI 10.1172/jci.insight.181481

mouseexperimental assay

𝕏 PostBluesky