Neural Stem Cells Secreting Bispecific T Cell Engager to Induce Selective Anti-Glioma Activity
K. C. Pituch, M. Zannikou, L. Ilut, T. Xiao, M. Chastkofsky, M. Sukhanova, N. Bertolino, D. Procissi, C. Amidei, C. Horbinski, K. S. Aboody, C. D. James, M. S. Lesniak, I. V. Balyasnikova
This study develops neural stem cells secreting a bispecific T cell engager (BiTE) to target glioblastoma, showing survival benefits in mice with IL13R2+ tumors.
bioRxiv · Jul 21, 2020Immunology